abstract：UNLABELLED:Medication adherence is a problem that has received widespread attention in the medical literature and health policy circles. With the increased emphasis on recognizing and rewarding quality in the U.S. health care system, medication adherence measures are increasingly being adopted to assess quality of medi...

journal_title：Journal of managed care & specialty pharmacy

authors： Sorensen TD,Pestka DL,Brummel AR,Rehrauer DJ,Ekstrand MJ

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Diabetes is a leading cause of morbidity, mortality, and medical resource utilization in the United States and worldwide. Treatment is aimed at keeping blood glucose levels close to normal and preventing or delaying medical complications. It has been estimated that only 50% of patients with diabetes in the U...

journal_title：Journal of managed care & specialty pharmacy

authors： Saundankar V,Peng X,Fu H,Ascher-Svanum H,Rodriguez A,Ali A,Slabaugh L,Young P,Louder A

更新日期：2016-05-01 00:00:00

abstract：:The AMCP Abstracts program provides a forum through which authors can share their insights and outcomes of advanced managed care practice through publication in AMCP's Journal of Managed Care & Specialty Pharmacy (JMCP). Most of the reviewed and unreviewed abstracts are presented as posters so that interested AMCP mee...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Formulary management within a limited budget is critical, especially for specialty drugs, which are used for serious medical conditions and are very expensive. Despite attempts to summarize the pertinent evidence, it is uncertain whether data needs of formulary decision makers for specialty drugs are satisfi...

journal_title：Journal of managed care & specialty pharmacy

authors： Choi Y,Navarro RP

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Prescription medication adherence is a known health-related barrier for elderly patients, leading to insufficient disease control and negative health outcomes. The Centers for Medicare & Medicaid Services (CMS) have placed significant emphasis on medication adherence, through the Part D star measures, revolv...

journal_title：Journal of managed care & specialty pharmacy

authors： Winters A,Esse T,Bhansali A,Serna O,Mhatre S,Sansgiry S

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Adherence to biologic disease-modifying antirheumatic drugs (bDMARDs) among patients with rheumatoid arthritis (RA) is often suboptimal in routine clinical practice. Low or nonadherence can reduce the effectiveness of bDMARD therapies. OBJECTIVE:To evaluate filling of newly prescribed initial bDMARDs for th...

journal_title：Journal of managed care & specialty pharmacy

authors： Harnett J,Wiederkehr D,Gerber R,Gruben D,Bourret J,Koenig A

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:All Department of Veterans Affairs Medical Centers (VAMCs) operate under a single national drug formulary, yet substantial variation in prescribing and spending exists across facilities. Local management of the national formulary may differ across VAMCs and may be one cause of this variation. OBJECTIVE:To c...

journal_title：Journal of managed care & specialty pharmacy

authors： Radomski TR,Good CB,Thorpe CT,Zhao X,Marcum ZA,Glassman PA,Lowe J,Mor MK,Fine MJ,Gellad WF

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:National guidelines and initiatives have promoted the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) for patients with diabetes. The University of Arizona Medication Management Center (UA-MMC) is contracted by Medicare health plans, pharmacy benefit managers ...

journal_title：Journal of managed care & specialty pharmacy

authors： Hurwitz JT,Grizzle AJ,Augustine J,Rehfeld R,Wild A,Abraham I

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Geographic variation in the use of prescription drugs, particularly those deemed harmful by the FDA, may lead to variation in patient exposure to adverse drug events. One such drug is the glucose-lowering drug rosiglitazone, for which the FDA issued a safety alert on May 21, 2007, following the publication o...

journal_title：Journal of managed care & specialty pharmacy

authors： Ahuja V,Sohn MW,Birge JR,Syverson C,Budiman-Mak E,Emanuele N,Cooper JM,Huang ES

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Acromegaly is a chronic disorder characterized by excess growth hormone secretion and elevated insulin-like growth factor-1 levels most often caused by a pituitary adenoma. Clinical presentation of the disease includes coarsening of the facial features, soft-tissue swelling of the hands and feet, and overgro...

journal_title：Journal of managed care & specialty pharmacy

authors： Placzek H,Xu Y,Mu Y,Begelman SM,Fisher M

更新日期：2015-12-01 00:00:00

abstract：:In a study published last year in the October 2014 issue of the Journal of Managed Care Specialty Pharmacy, Trivedi et al. compared treatment patterns of dasatinib and nilotinib as second-line tyrosine kinase inhibitors (TKI) therapy in chronic myeloid leukemia (CML) patients during the first year of treatment.1 Trive...

journal_title：Journal of managed care & specialty pharmacy

authors： Chen L,Wu EQ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Allergy immunotherapy (AIT) is the only available treatment that alters the natural course of allergies and has possible disease-modifying effects. AIT is administered primarily via subcutaneous injection delivered in a physician's office. Few studies have been conducted in the United States or Canada to eva...

journal_title：Journal of managed care & specialty pharmacy

authors： Blume SW,Yeomans K,Allen-Ramey F,Smith N,Kim H,Lockey RF,Nichol MB

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Prescription opioid abuse is associated with substantial economic burden, with estimates of incremental annual per-patient health care costs of diagnosed opioid abuse exceeding $10,000 in prior literature. A subset of patients diagnosed with opioid abuse has disproportionately high health care costs, but lit...

journal_title：Journal of managed care & specialty pharmacy

authors： Shei A,Rice JB,Kirson NY,Bodnar K,Enloe CJ,Birnbaum HG,Holly P,Ben-Joseph R

更新日期：2015-10-01 00:00:00

abstract：:We write to comment on a recently published study by Delea et al. in the January 2015 issue of JMCP that evaluated the cost-effectiveness (CE) of sunitinib (SU) versus pazopanib (PAZ) as first-line treatment for metastatic renal cell carcinoma (mRCC) from a U.S. third-party payer perspective.1 This analysis was based ...

journal_title：Journal of managed care & specialty pharmacy

authors： Benedict A,Ramaswamy K,Sandin R

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Accurate estimates of the effects of cost sharing on adherence to medications prescribed for use together, also called concurrent adherence, are important for researchers, payers, and policymakers who want to reduce barriers to adherence for chronic condition patients prescribed multiple medications concurre...

journal_title：Journal of managed care & specialty pharmacy

authors： Sacks NC,Burgess JF,Cabral HJ,McDonnell ME,Pizer SD

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:In recent years, there have been a number of pharmacological innovations for Crohn's disease (CD), a difficult-to-treat condition, including new treatment philosophies (e.g., top-down therapy) and new therapeutic options in terms of the agent and the route of administration. Three anti-tumor necrosis factor ...

journal_title：Journal of managed care & specialty pharmacy

authors： Liu J,Sylwestrzak G,Ruggieri AP,DeVries A

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Concomitant use of stimulants and atypical antipsychotics is common in pediatric attention deficit hyperactivity disorder (ADHD). However, little is known about the determinants of concomitant use and its utility in the management of pediatric ADHD. OBJECTIVES:To (a) examine predictors of concomitant stimul...

journal_title：Journal of managed care & specialty pharmacy

authors： Bali V,Kamble PS,Aparasu RR

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Poor medication adherence is a predictor of poor health outcomes, especially in populations with chronic diseases. Although several self-reported measures of medication adherence exist, the scope of each is limited.  OBJECTIVE:To identify barriers to medication adherence in order to facilitate effective del...

journal_title：Journal of managed care & specialty pharmacy

authors： Hincapie AL,Taylor AM,Boesen KP,Warholak T

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Value-based insurance design attempts to align drug copayment tier with value rather than cost. Previous implementations of value-based insurance design have lowered copayments for drugs indicated for select "high value" conditions and have found modest improvements in medication adherence. However, these im...

journal_title：Journal of managed care & specialty pharmacy

authors： Sullivan SD,Yeung K,Vogeler C,Ramsey SD,Wong E,Murphy CO,Danielson D,Veenstra DL,Garrison LP,Burke W,Watkins JB

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Natalizumab disease-modifying therapy for relapsing-remitting multiple sclerosis (MS) is efficacious in randomized controlled trials. Few studies have estimated the association between real-world natalizumab persistence behavior and relapse-related outcomes. OBJECTIVES:To (a) examine the impact of using nat...

journal_title：Journal of managed care & specialty pharmacy

authors： McQueen RB,Livingston T,Vollmer T,Corboy J,Buckley B,Allen RR,Nair K,Campbell JD

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) are a mainstay of treatment for patients suffering from chronic myeloid leukemia (CML). Testing for various mutations in the BCR-ABL gene may help predict lack of response to specific TKIs where resistance has developed. OBJECTIVE:To estimate the emergence of BCR-ABL kinase...

journal_title：Journal of managed care & specialty pharmacy

authors： Ursan ID,Jiang R,Pickard EM,Lee TA,Ng D,Pickard AS

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The Biologics Price Competition and Innovation Act, introduced as part of the Affordable Care Act, directed the FDA to create an approval pathway for biologic products shown to be biosimilar or interchangeable with an FDA-approved innovator drug. These biosimilars will not be chemically identical to the refe...

journal_title：Journal of managed care & specialty pharmacy

authors： AMCP Task Force on Biosimilar Collective Intelligence Systems.,Baldziki M,Brown J,Chan H,Cheetham TC,Conn T,Daniel GW,Hendrickson M,Hilbrich L,Johnson A,Miller SB,Moore T,Motheral B,Priddy SA,Raebel MA,Randhawa G,Surratt

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Encouraging generic drug use has reduced health care costs for payers and consumers, but the availability of therapeutically interchangeable medications or generic medications of choice is not equal across disease states. The extent to which systems of care are able to substitute with generics is not well un...

journal_title：Journal of managed care & specialty pharmacy

authors： Walton SM,Rash C,Lambert BL,Galanter WL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is associated with substantial morbidity and mortality. With the rise in prevalence of diabetes, there has been an increased need for clinical pharmacy services focused on diabetes management in ambulatory clinics. However, more data IS needed to determine the overall impact that clinical p...

journal_title：Journal of managed care & specialty pharmacy

authors： Chung N,Rascati K,Lopez D,Jokerst J,Garza A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The implementation of Medicare Part D provided insurance coverage for outpatient medications, but when persons reach the "gap," they have very limited or no medication insurance coverage until they reach a second threshold for catastrophic coverage. In addition, some patients have a low-income subsidy (LIS),...

journal_title：Journal of managed care & specialty pharmacy

authors： Park H,Rascati KL,Lawson KA,Barner JC,Richards KM,Malone DC

更新日期：2014-08-01 00:00:00

abstract：:Improving medication adherence has been identified as a crucial step towards improving health outcomes for patients with chronic disease and has provided the motivation for many changes in our health care system. Despite the volume of research done on this topic, however, we still lack important basic information abou...

journal_title：Journal of managed care & specialty pharmacy

authors： Seabury SA,Gupta CN,Philipson TJ,Henkhaus LE,PhRMA Medication Adherence Advisory Council.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Cancer is a major cause of mortality and a major contributor to health care costs in the United States. An increasing number of cancer patients are treated with oral cancer therapy. Older patients are more likely to have cancer and to be at risk for adherence problems with oral cancer drugs. As a result of s...

journal_title：Journal of managed care & specialty pharmacy

authors： Kaisaeng N,Harpe SE,Carroll NV

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Rosacea is a chronic skin disorder that presents with abnormal vascular and inflammatory conditions. Clinical manifestations include flushing, facial erythema, inflammatory papules and pustules, telangiectasias, edema, and watery or irritated eyes. OBJECTIVE:To discuss the evolving pathophysiology of rosace...

journal_title：Journal of managed care & specialty pharmacy

authors： Feldman SR,Huang WW,Huynh TT

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Adjuvant trastuzumab treatment is administered to early stage breast cancer patients in physician office (POV) or hospital outpatient (HOP) settings. OBJECTIVE:To identify treatment patterns, utilization, and costs by site of care (POV vs. HOP) of patients with adjuvant treatment of breast cancer with trast...

journal_title：Journal of managed care & specialty pharmacy

authors： Parthan A,Santos E,Becker L,Small A,Lalla D,Brammer M,Teitelbaum A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Immunoglobulin (Ig) is a costly blood product prescribed as immune replacement or modulation therapy to treat a wide spectrum of medical conditions. While the FDA has approved Ig for a limited number of indications, there are multiple off-label uses that have demonstrated proven clinical benefit or are curre...

journal_title：Journal of managed care & specialty pharmacy

authors： Tonkovic B,Rutishauser LK

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:While there is growing demand for information about comparative effectiveness (CE), there is substantial debate about whether and when observational studies have sufficient quality to support decision making. OBJECTIVE:To develop and test an item checklist that can be used to qualify those observational CE ...

journal_title：Journal of managed care & specialty pharmacy

authors： Dreyer NA,Velentgas P,Westrich K,Dubois R

更新日期：2014-03-01 00:00:00